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What if you were a problem drinker or alcoholic, plus a medical professional could give you a drug to consider away your urge to drink—while you're still allowed to continue drinking? Advocates of the treatment approach, called the Sinclair method, claim you'd likely experience no withdrawal symptoms. According to proponents, after three or four months on the medication, all while still being in a position to continue to drink, you'd experience diminished cravings as well as find that your urge to drink disappears.

Using two separate drugs to lose weight naturally can be very effective there are combinations as you're watching FDA now awaiting approval. When dealing with weight reduction and the individuals who go through it you need to err to the side of caution and let the FDA do its job and demand some research be done in order that the public understands the side effects and hazards of the medications before we bring them. Keep in mind that drug companies are in business to generate income and that they would say anything to keep people on his or her medications.

Researchers discovered that participants investing in this drug for the year, lost weight within four weeks and have kept the body weight off through the entire 56 weeks of the study. Contrave can be a combination in the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs which are made up of many active ingredient, that might make them more efficient and safer.

Combo-pilling may be the newest fad or better yet the newest ahead under scrutiny and thus it is just more publicly known in recent months, comb-pilling for weight reduction has been around since the eighties. The biggest reason that by using a combination of pills is starting to become popular is the fact that as of right now there are not any long term prescription slimming capsules that have been authorized by the FDA apart from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications and some of the combinations happen to be rejected or have yet to be licensed by the FDA.

Seizures really are a side effect with Contrave and really should not be taken in people who have seizure disorders. The drug could also raise blood pressure and heartrate, and shouldn't be used in individuals with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy while using drug.

The FDA also warned that Contrave can raise hypertension and pulse rate and must 't be used in patients with uncontrolled high blood pressure level, in addition to by anyone with heart-related and cerebrovascular (blood vessel dysfunction impacting the brain) disease. Patients which has a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes which has a boxed warning to alert physicians and patients for the increased risk of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stop smoking.


Approving a drug using this many potentially lethal side effects is inconsistent with all the mission statement from the FDA. The power of the drug manufacturing lobby is blatantly evident in the approval of numerous drugs requiring 'post-marketing' studies which might be clearly significant to overall drug safety inside US.